These products include bottles, pipes, plastic containers, insulated wires, clothing, toys, and non-stick pans. Actively scan device characteristics for identification. Use precise geolocation data. Select personalised content. Create a personalised content profile. Measure ad performance. Select basic ads. Create a personalised ads profile. Select personalised ads. Apply market research to generate audience insights. Measure content performance. Develop and improve products.
List of Partners vendors. Share Flipboard Email. Shirbin, S. Effects of side group functionality and molecular weight on the activity of synthetic antimicrobial polypeptides. Biomacromolecules 12 , — Ahmed, M. Peptides, polypeptides and peptide—polymer hybrids as nucleic acid carriers.
Chen, J. Cheng, Y. Miyata, K. Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses. Mutaf, O. Induction of secondary structure through micellization of an oppositely charged pair of homochiral block- and homopolypeptides in an aqueous medium. Perry, S. Chirality-selected phase behaviour in ionic polypeptide complexes.
Gabrielson, N. A cell-penetrating helical polymer for siRNA delivery to mammalian cells. Wang, H. Yin, L. Non-viral gene delivery via membrane-penetrating, mannose-targeting supramolecular self-assembled nanocomplexes. He, H. Suppression of hepatic inflammation via systemic siRNA delivery by membrane-disruptive and endosomolytic helical polypeptide hybrid nanoparticles.
ACS Nano 10 , — Liu, Y. Nanoscale 10 , — Light-responsive helical polypeptides capable of reducing toxicity and unpacking DNA: toward nonviral gene delivery. Zheng, N. Manipulating the membrane penetration mechanism of helical polypeptides via aromatic modification for efficient gene delivery. Acta Biomater. Li, F. ACS Appl. Interfaces 9 , — Dang, J. Multivalency-assisted membrane-penetrating siRNA delivery sensitizes photothermal ablation via inhibition of tumor glycolysis metabolism.
Biomaterials , Therapeutic protein—polymer conjugates: advancing beyond PEGylation. Hou, Y. Therapeutic protein PEPylation: the helix of nonfouling synthetic polypeptides minimizes antidrug antibody generation. Zhang, C. Biomaterials , — Cabral, H. Progress of drug-loaded polymeric micelles into clinical studies. Release , — Block copolymer micelles in nanomedicine applications.
Olsen, B. Self-assembly of rod—coil block copolymers. Holowka, E. Charged polypeptide vesicles with controllable diameter. Polyarginine segments in block copolypeptides drive both vesicular assembly and intracellular delivery. Choe, U. Endocytosis and intracellular trafficking properties of transferrin-conjugated block copolypeptide vesicles. Biomacromolecules 14 , — Schatz, C. Polysaccharide- block -polypeptide copolymer vesicles: towards synthetic viral capsids.
Upadhyay, K. Biomaterials 31 , — Quadir, M. Clickable synthetic polypeptides—routes to new highly adaptive biomaterials. Ligand-decorated click polypeptide derived nanoparticles for targeted drug delivery applications. Nanomedicine 13 , — Mochida, Y. Bundled assembly of helical nanostructures in polymeric micelles loaded with platinum drugs enhancing therapeutic efficiency against pancreatic tumor. Demonstrates that the helical conformation can be induced upon loading of a drug, improving not only the mechanical properties of the formed micelles but also their pharmaceutical properties.
Accumulation of sub nm polymeric micelles in poorly permeable tumours depends on size. Peppas, N. Nowak, A. Rapidly recovering hydrogel scaffolds from self-assembling diblock copolypeptide amphiphiles. Demonstrates that the helical conformation has a significant impact on the mechanical properties of synthetic hydrogels, paving the way to the application of these materials for tissue engineering and drug delivery.
Breedveld, V. Rheology of block copolypeptide solutions: hydrogels with tunable properties. Macromolecules 37 , — Polypeptide hydrogels via a unique assembly mechanism. Soft Matter 1 , 28—35 Zhang, S. Design and synthesis of nonionic copolypeptide hydrogels with reversible thermoresponsive and tunable physical properties. Biomacromolecules 16 , — Wollenberg, A.
Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery. Anderson, M. Astrocyte scar formation aids central nervous system axon regeneration. Required growth facilitators propel axon regeneration across complete spinal cord injury.
Schwartz, E. Helical poly isocyanides : past, present and future. Akeroyd, N. Kollmar, C. Polyisocyanides: electronic or steric reasons for their presumed helical structure? Clericuzio, M. Theoretical investigations on the structure of poly iminomethylenes with aliphatic side chains.
Conformational studies and comparison with experimental spectroscopic data. Hase, Y. Mechanism of helix induction in poly 4-carboxyphenyl isocyanide with chiral amines and memory of the macromolecular helicity and its helical structures.
Cornelissen, J. Science , — Describes the preparation of poly isocyanide s with stable helicity in aqueous conditions as a result of the H-bond network formed between the peptide side chains.
Kouwer, P. Responsive biomimetic networks from polyisocyanopeptide hydrogels. Das, R. Stress-stiffening-mediated stem-cell commitment switch in soft responsive hydrogels. Cytoskeletal stiffening in synthetic hydrogels.
Thermosensitive biomimetic polyisocyanopeptide hydrogels may facilitate wound repair. Helical superstructures from charged poly styrene -poly isocyanodipeptide block copolymers. Vriezema, D. Vesicles and polymerized vesicles from thiophene-containing rod—coil block copolymers. Reports the use of poly isocyanide s to prepare block copolymers that can afford vesicles in both organic and aqueous conditions, as a result of the unique solubility of the poly isocyanide block and its helical conformation.
Cascade reactions in nanoreactors. Che, H. Adaptive polymersome nanoreactors. ChemNanoMat 5 , — Positional assembly of enzymes in polymersome nanoreactors for cascade reactions. A three-enzyme cascade reaction through positional assembly of enzymes in a polymersome nanoreactor.
Enhanced lubrication on tissue and biomaterial surfaces through peptide-mediated binding of hyaluronic acid. Kelich, J. Super-resolution imaging of nuclear import of adeno-associated virus in live cells. Google Scholar.
Goldsmith, C. Modern uses of electron microscopy for detection of viruses. Sachse, C. High-resolution electron microscopy of helical specimens: a fresh look at tobacco mosaic virus. Vestergaard, G. Bharat, T. Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography. Virology: independent virus development outside a host. Nature , — Jiang, X. Plasmid-templated shape control of condensed DNA-block copolymer nanoparticles. This paper establishes that the shape of polymeric, plasmid DNA-containing nanoparticles can be controlled by solvent polarity, and that anisotropic biomimetic particles can have enhanced gene-delivery efficacy in vivo.
Hanson, M. Antigen delivery by lipid-enveloped PLGA microparticle vaccines mediated by in situ vesicle shedding. Biomacromolecules 15 , — Roberts, R. Towards programming immune tolerance through geometric manipulation of phosphatidylserine. Biomaterials 72 , 1—10 Perry, J. PRINT: a novel platform toward shape and size specific nanoparticle theranostics. Hu, C. Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform. This paper uses cell membranes to camouflage and functionalize polymeric nanoparticles, opening the door to new hybrid biomimetic particles.
Fang, R. Cancer cell membrane-coated nanoparticles for anticancer vaccination and drug delivery. Nano Lett. Nanoparticle biointerfacing by platelet membrane cloaking. A biomimetic nanosponge that absorbs pore-forming toxins. Nature Nanotechnol.
Parodi, A. Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions. Xuan, M. Macrophage cell membrane camouflaged mesoporous silica nanocapsules for in vivo cancer therapy. Healthcare Mater. Lai, P. Biomimetic stem cell membrane-camouflaged iron oxide nanoparticles for theranostic applications.
RSC Adv. Rodriguez, P. Minimal 'self' peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles. Tsai, R. Self inhibition of phagocytosis: the affinity of 'marker of self' CD47 for SIRPalpha dictates potency of inhibition but only at low expression levels.
Blood Cells Mol. Sosale, N. Blood , — Wilhelm, S. Analysis of nanoparticle delivery to tumours. Meyer, R. Biodegradable nanoellipsoidal artificial antigen presenting cells for antigen specific T-cell activation.
Small 11 , — Perica, K. Enrichment and expansion with nanoscale artificial antigen presenting cells for adoptive immunotherapy. ACS Nano 9 , — Sunshine, J. Biomaterials 35 , — Lashof-Sullivan, M. Intravenously administered nanoparticles increase survival following blast trauma. Anselmo, A. Suppose, on the other hand, that the catalysts were mass-produced.
Joining the amino acids to each other by a common mechanism allows a single catalyst to join 20 different amino acids by the same chemical reactions. Because a single protein may contain 1, or more amino acids joined end to end, a huge number of different catalysts can be made from the relatively few monomer compounds. Previous Common Themes in Biochemistry.
0コメント